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Search Portfolio Projects and Investments
County Impact Map
268 Entries Found
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Organization / Applicant |
Project Description |
Focus Area |
Award |
Fund |
Intrucept Biomedicine, LLC
Daniel Tuse
County |
Plant-based manufacturing of novel antiviral drug
Intrucept Biomedicine’s mission is to develop and commercialize broad-spectrum antiviral therapeutics. The technology Intrucept is developing is based on a new class of proteins that can prevent viral infection. Intrucept has discovered that its lead molecules can be preferentially manufactured using plant-based biotechnologies. The Company has formed a strategic alliance with Kentucky Bioprocessing, LLC (Owensboro, KY), to leverage the scalability and cost advantages offered by KBP’s process resources, together with Intrucept’s proprietary products, into a strong competitive position. Funding from KSTC will be applied to manufacture the Company’s lead product for preclinical evaluation.
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Biosciences
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$25,000
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Rural Level 1 |
RevStream, LLC
Barbara Wagner
Boyd County |
Compressed oxygen
Patented new technology for delivery of compressed oxygen to the home health care market
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Biosciences
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$7,500
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Rural Level 1 |
Robot Crafters, LLC
Robert Pilgrim
Calloway County |
A system and method for weed identification and plant-specific herbicide application.
Robot Crafters, LLC of Murray, KY has been awarded a Rural Level 1 grant for the development and commercialization of a new and innovative system for weed control in commercial agriculture. This system uses machine vision techniques to recognize the difference between weeds and crop plants. This system applies herbicide in a plant-specific manner that permits post-emergence herbicide use in non-herbicide resistant crops. This plant-specific herbicide application system eliminates practically all issues of drift and run-off, it significantly reduces the quantity of herbicide needed to control weeds, and it supports the use of a wider variety of types of herbicides.
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Biosciences
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$25,000
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Rural Level 1 |
ChemClark Inc.
Heinz Kohler
Clark County |
Custom Chemical Synthesis Technique
Validation of ChemClark’s Antibody Crosslinker for therapeutic purposes.
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Biosciences
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$18,500
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Rural Level 1 |
NanoMed Pharmaceuticals, Inc.
Stephen Benoit
Fayette County |
Nanoparticle based drug delivery systems
Pharmaceuticals company developing novel nanoparticle-based CNS drug and vaccine delivery systems to deliver drugs to the brain, and to create “next generation” vaccines.
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Biosciences
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$24,912
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ICC |
Topical Analgesic Concepts, LLC
Steven Mobley
Fayette County |
A synthesized derivative of salicylic acid previously found only in nature, used as a topical analgesic
Topical Analgesic Concepts, LLC represents a patented synthetic derivative of aspirin previously occurring only in nature. Current topical pain relief products are categorized as "counter irritants", only masking the pain. This compound exhibits chemical characteristics supporting a superior ability to be absorbed through the skin to the cause of pain.
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Biosciences
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$30,000
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KEF Grant |
IP Pharmaceuticals, LLC
Guangxiang (George) Luo
Fayette County |
Technologies and antiviral therapeutics against viral infections
Hepatitis C virus (HCV) infection poses a major global health problem affecting nearly 4 million Americans and 170 million people worldwide. Interferon (IFN) in combination with ribavirin is the only option for treating HCV infection. However, IFN/ribavirin therapy suffers from a limited efficacy and severe unwanted side effects. We have discovered new classes of potent antiviral agents against HCV replication, including monoclonal antibody and small interfering RNA (siRNA) specifically against a human lipoprotein. We also identified a natural product that potently inhibits HCV replication. We will further determine the safety and efficacy of these antiviral agents for treating hepatitis C.
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Biosciences
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$25,000
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ICC |
Tribo Flow Separations LLC.
John Stencel
Fayette County |
Instrumentation for real-time monitoring and identifying microbes and cells
The capacity to develop the first real-time biosensor is created. Called the microbe and cell assay (MICA™) device, it determines the presence and activity of bacteria, viruses and cells by detecting inherent physical and chemical processes of and interactions between microbes and cells. MICA™ provides microbiological information for clinical and research applications, including the detection of microbes even at very low concentrations; characterization of cell cultures useful for discovery of novel drugs; measurement of virus-cell interactions during viral attack; and real-time definition of intra-cellular and extra-cellular sensing and communication that occurs during the onset of bacterial and viral infections.
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Biosciences
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$25,000
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ICC |
ALT BioScience (TOPAS)
Angie Chapman
Fayette County |
Provide third party clinical studies to validate clinical utility of TOPAS, thereby increasing market penetration.
TOPAS was developed and designed for the detection and quantification of oral anearobic bacterial by-products and inflammatory proteins to aid in the measurement of progression or remission of periodontal disease. Phase I trials will involve Temple University School of Dentistry to validate TOPAS with standard periodontal disease diagnostics. Over a two month period, the study will include three distinct patient groups: healthy patients, patients with gingivitis and patients with periodontitis. Statistical analysis will look at the correlation of TOPAS to standard diagnostics, including differences between the three patient types.
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Biosciences
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$25,000
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ICC |
NeoCytex Biopharma, Inc.
Nilabh Chaudhary
Fayette County |
development of a drug to treat stroke and other neurodegenerative diseases
NeoCytex's long-term goal is to discover and develop novel regenerative pharmaceuticals that can accelerate recovery from neural diseases and injuries, either as stand-alone therapy or in combination with other treatments. Our lead drug candidate is a treatment for stroke, one of the major causes of death and disability in the United States. The small molecule compound works via a novel mechanism to accelerate the production of new brain cells from preexisting neural stem cells in the brain. Our plan is to scale up the production of the compound and conduct animal efficacy and safety studies leading up to human testing.
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Biosciences
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$25,000
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ICC |
ALT Bioscience (Smart Breath)
Angie Chapman
Fayette County |
Provide primary market research for the launch of the company's consumer product, Breath Detect
Minneapolis based Heinrich Marketing Research Firm and Leapfrog Associates will conduct qualitative and quantitative primary market research across the U.S. market place to ascertain regional and socioeconomic differences regarding halitosis (bad breath), price point, and various demographic data. The primary purpose of this research is to help identify viable markets and gain consumer feedback prior to the launch of Breath Detect. Primary Market research is scheduled to be conducted in 3Q of 2007. This market research project will also help ascertain concept appeal and positioning strategies for the marketplace, as well as optimum geographic regions and retail outlets for launch.
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Biosciences
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$25,000
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ICC |
Advanced Genomic Technology, LLC
Eugenia Wang
Jefferson County |
MICRO-RNA MICROARRAY AND METHODS OF MICRO-RNA PROFILING (including library development and integration)
AGT was recently formed to focus on commercialization of technologies currently in development at the University of Louisville under the direction of Eugenia Wang, Ph.D., AGT’s founder and CSO. Development of the technology has been supported by grants totaling more than $1,000,000. The Company plans to accelerate commercialization strategies over the next 6 months with manufacturing and first sales within 18 months. AGT’s technology makes it possible to identify the mechanism of specific changes of physiological state and to directly identify and study the particular cellular state. The information can then be linked to the robust proprietary library and provide for testing and use of targeted therapeutics, diagnostics, and drug screenings.
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Biosciences
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$25,000
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ICC |
International Performance Registry
Charles Buddeke
Jefferson County |
Animal identification and tracking system based on iris recognition.
IPR is developing patentable, non-invasive products and services that capture, authenticate, track and distribute data throughout the life of an animal through the exclusive use of a biometric platform technology known as “iris recognition.” IPR’s unique products have the ability to non-invasively identify an animal then access and/or update its historical information. The company will combine iris identification, automated transaction processing, security, databases, the Internet, and other technologies to create innovative, useful and commercially viable products and services under its IrisTrac™ brand.
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Biosciences
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$25,000
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ICC |
Advanced Cancer Therapeutics (ACT) LLC
Randall Riggs
Jefferson County |
Demonstrate through extensive animal toxicology studies that 3PO is safe for human clinical trials.
Novel anti-cancer product, 3PO, demonstrated anti-cancer activity in five (5) different in vivo cancer models including solid and blood related cancers. ACT, with the financial assistance from KSTC, will move forward to extensively test the safety of 3PO in various animals studies in preparation of entering human clinical trials with 3PO as a novel and promising treatment for cancer patients.
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Biosciences
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$25,000
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ICC |
Biologics International, Inc.
Amy Miles
Kenton County |
Yeast-based cosmetic products
Bluegrass Laboratories is not only providing its customers with quality skin care products containing the finest of active ingredients, but also a unique way of providing customer assistance in a comfortable, convenient environment.
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Biosciences
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$25,000
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Rural Level 1 |
Anavasis Pharmaceuticals
Paul Whitley
Logan County |
Drug Formulation
Business plan development for Anavasis Pharmaceuticals, a startup pharmaceutical contract research and development company.
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Biosciences
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$7,500
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Rural Level 1 |
Nano-Mite Technologies LLC
Greg Johnson
Scott County |
Address the obesity issue in humans and animals.
Nano-Mite Technologies, LLC has developed nano technology and tested this technology in rats with excellent results. With these results in hand we have, in conjunction with the University of Kentucky, filed a patent with the U.S. Patent Office in May of 2006 along with a PCT for international protection. A license agreement has been signed between UK, who owns the Intellectual Property, and Nano-Mite Technologies LLC. Laboratory testing has continued and we have leased space in the UK ASteCC facility. Currently we are negotiating with a pharmaceutical company for continued testing in animals. Our current objective is to prove the concept in Lap Animals (Dogs and Cats). It is our understanding that the market for diet supplements for lap animals in the US alone approaches 500 million per year. We intend to enter this market during the testing phase in humans.
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Biosciences
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$25,000
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ICC |
Laura-Katherine Company
Kimberly Halter
Warren County |
Environmental friendly fly compound that eliminates toxic and messy fly devices and chemicals.
Discovered a unique property of an existing product that could expand its market into pest termination.
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Biosciences
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$7,500
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Rural Level 1 |
Ballad Enterprises, Inc.
Eugene Tatum
Warren County |
Medical Products: biopsy specimens
Medical device for organizing specimens from multi-biopsy procedures.
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Biosciences
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$7,500
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Rural Level 1 |
ECM Biosciences, LLC
Mark Wilson
Woodford County |
Antibody development company.
ECM Biosciences is a company that develops novel biotechnologies for life science research. Our company works in collaboration with research institutions worldwide to develop innovative tools for the advancement of research and therapies related to neuropathology, cancer, immune dysfunction and cardiovascular disease.
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Biosciences
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$24,550
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Rural Level 1 |
Union County Biodiesel Company
George Sprague
Union County |
Biodiesel fuel alternative
Utilizes a soy-based biodiesel fuel that reduces dependence on foreign oil, harmful emissions, and improves engine performance. UCBC's technology reduces production costs and yields no harmful by-products.
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Environmental and Energy Technologies
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$17,500
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Rural Level 1 |
Storm Shields, LLC
Laurie Hendren
Nelson County |
Cover for a home to protect against water, wind and certain types of gasses.
Storm Shield, LLC introduces a new and innovated product to protect homes in hurricane prone areas. This product will prevent flooding to homes and will reduce the winds coming into the home by up to 4x. This product will be manufactured in Kentucky and the Company will employ over 400 employees. Currently it has been tested to prevent fire damage to homes in fire prone areas. The product has also been tested to a fire resistant temperature of 1500 F. Our product will affect over 5 million people in the U.S. and over 15 million people world wide. It is estimated to save million of dollars in property damage and countless lives yearly. Over the past seven years or so, hurricane activity has dramatically increased in the Atlantic Basin. Since 1995, we have seen a total of 79 named storms, 43 hurricanes, and 25 major hurricanes. That is supposedly just a sign of things to come as many forecaster and hurricane experts predict that we have just begun to enter a period of increased hurricane activity in the Atlantic.
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Environmental and Energy Technologies
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$25,000
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Rural Level 1 |
JOHN CARTER IMAGINEERING
John Carter
Mercer County |
New siphon pump technology
The AUTOSIPHON concept is a significant breakthrough in siphon technology to control flow, retain prime, and dispense above the source. This technology represents the first true siphon pump.
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Environmental and Energy Technologies
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$8,500
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Rural Level 1 |
Louisville Clean Energy, LLC
Bill Bivins
Jefferson County |
Biorefinery that produces ethanol, biodiesel, electricity, and syngas independent of fossil fuels
Louisville Clean Energy (LCE) is a limited liability company focused on producing renewable energies consisting of the production/generation of biogas, electricity, bio-diesel, and ethanol production. The LCE pilot project is a 3 phase project; Phase 1 – biogas generation from organic waste; Phase 2 –Bio-Diesel from used cooking oil unrefined; Phase 3 – ethanol production from corn, wheat and sorghum feedstock.
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Environmental and Energy Technologies
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$25,000
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ICC |
GreenerWay LLC.
Josh Beatty
Jefferson County |
GreenerWay is an innovative energy monitoring and management solution helping users conserve energy.
The way we use and pay for electricity causes many consumers to spend without thinking. Actually seeing the cost of turning an appliance on or off can have a dramatic effect on consumption. Research shows that monitoring electricity use can result in a 25 percent reduction in energy use. GreenerWay empowers users and allows them to actively manage and conserve energy while easing the burden of their rising utility bill. GreenerWay is more than just a money and energy saving product; it brings energy conservation issues to the forefront of consumers’ computer desktops and thus their lives.
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Environmental and Energy Technologies
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$25,000
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ICC |
Vortecone LLC
James Boyd
Fayette County |
Vortecone has licensed vortex chamber technology (developed by UK and Toyota) for non-automotive applications. The company intends to use the technology to treat waste in industrial applications – especially treatment of coal-fired electric plants.
Vortecone LLC will examine the feasibility of adapting its paint booth overspray capture technology for use in emission control for coal-fired power plants. This product is currently being used by Toyota in five of their plants worldwide.
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Environmental and Energy Technologies
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$25,000
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ICC |
Gryphon Environmental, LLC
W. Tid Griffin
Hancock County |
filter processing system for mixed water and water and waste streams
New patented technologies and science enable Gryphon Environmental to take the municipal and industrial effluents (mixed water and waste) and dehydrate them into reusable materials and fuels. As mixed water and wastes, these effluents are currently leaked into our natural environment and costs billions of dollars to manage. Gryphon Environmental technology has new mechanics and science to seperate cleaned water from dry solid wastes. The innovative system enables dry waste yields to exceed 50% dry solid content for the first time, resulting in lower hauling costs and the ability for these wastes to be utilized as combustible coal dust substitutes and fabrication components. Treated waters are safely returned to the environment, reused in industry or used as nutrient-rich waters for growing algae. These algae strains are high in lipids and are ideal for the creating of high volumes of biodeisel fuels.
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Environmental and Energy Technologies
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$25,000
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Rural Level 1 |
Wind Energy Corporation
Michele Hilbig
Hardin County |
Develop and commericialize an off grid wind harvesting device to power commericial applications
Headquartered in Elizabethtown, KY, Wind Energy Corporation is a leader in the advancement of commercial and community wind applications. Wind Energy Corp has been awarded a grant from the State of Kentucky’s “Kentucky Enterprise Fund” to demonstrate the capability of its wind turbine which utilizes a unique design and complex composite materials, creating greater possibilities for sustainable energy systems in the marketplace.
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Environmental and Energy Technologies
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$25,000
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Rural Level 1 |
Gersony Medical Media, Inc. (dba Medmovie.com)
Richard Gersony
Fayette County |
Creation of a business plan for marketing and expansion of Medmovie’s patient education Media Library
Medmovie creates animated medical education tools for professionals and patients. Medmovie’s Media Library System is a software and database of animated medical media. It provides a “visual dictionary” of terms for patients and healthcare providers. Media can be integrated into websites or tailored within electronic medical records (EMR) or patient health records (PHR). Medmovie cardiovascular content is licensed to hospitals, non-profits, government and corporations with proposed expansion into PHR and EMR markets. With funded support, Medmovie staff and world-renowned consultants will create a business plan with market analysis and plans for marketing and future growth.
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Human Health and Development
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$25,000
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ICC |
Solution Cap, LLC
Lisa Carr
Hardin County |
Hair cap designed to prevent leakage of hair treatment solutions
This device will provide a much needed solution in the hair perming process that will increase comfort level for clients and provide for ease of use by beauty professionals.
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Human Health and Development
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$25,000
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Rural Level 1 |
OTC Solutions
Richard Timberlake
Greenup County |
Over The Counter treatments for the self-medicating market
OTC Solutions will provide the OTC industry with their own brand of unique alternatives to the antiquated products currently available through Retail, Wholesale and Clinical use.
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Human Health and Development
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$25,000
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Rural Level 1 |
Cymbion, LLC
Vinod Narula
Jefferson County |
Patented anti-infection solution and applicators.
Patented a waterless anti-infection solution, which substantially improves the effectiveness of the pre-surgical hand santizing, as well as a pre-surgical scrub brush with enhanced ergonomical design.
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Human Health and Development
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$25,000
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ICC |
Partum Group LLC
Divya Cantor
Jefferson County |
MaternaTRAC™ will measure and quantify the changes of the cervix through the labor course.
The Partum Group is developing the MaternaTRAC™, a medical device that quantifies precisely the changes of a woman’s cervix as she progresses through labor. Traditionally this has been a subjective measurement prone to error. The MaternaTRAC™ will help identify adequate inductions of labor, reduce missed deliveries, identify pre-term labor and create alarms for risk factors. Use of the MaternaTRAC™ will provide for improved physician diagnosis and treatment and better management of labor and delivery units by hospitals, including lower liability costs and fewer errors.
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Human Health and Development
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$25,000
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ICC |
ImmunoTheragnostics Incorporated
Andrew Steen
Jefferson County |
Method for the early detection of ovarian cancer.
ImmunoTheragnostics Incorporated is developing innovative products for women’s health. Currently the company is focused on the development of serum-based diagnostic tests—including tests for women specific cancers and non-malignant conditions, such as infertility and pregnancy complications. ImmunoTheragnostics’ lead diagnostic program is in ovarian cancer. Ovarian cancer is the 4th leading cause of cancer-related deaths in women. From a patient serum sample, the company’s test will be able to: identify the presence of ovarian cancer, provide information on the stage of disease and allow optimization of treatment regimens.
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Human Health and Development
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$25,000
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ICC |
Mindstreet LLC
Jesse Wright
Jefferson County |
Development of effective computer program for treatment of depression and anxiety
Significant enhancements will be made to computer software that has already been shown to be an effective treatment for clinical depression and anxiety. These enhancements will create a full program of computer-assisted interventions which will be used by mental health clinicians to increase the efficiency and decrease the cost of treatment. There is a great need for economical psychiatric treatments that are effective and can reach many people. Computer-assisted treatment with the software developed with this award has great potential for improving the efficacy of therapy and increasing access to needed services.
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Human Health and Development
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$25,000
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ICC |
SureGene, LLC
Mark Brennan
Jefferson County |
CLIA validation of AssureGene Test for Schizophrenia as a precursor to product launch.
In order to launch a genetic test in the US under the "home brew" exemption, the test must be validated analytically at a High Complexity Test facility approved by CLIA (Clinical Laboratory Improvement Amendments). SureGene has accumulated sufficient scientific data to support the launch of the AssureGene test for risk assessment in schizophrenia. Management has identified a CLIA-certified lab that will conduct the validation of the test and act as a service provider for the initial commercial launch of the product. The AssureGene test will be the first commercial test for schizophrenia.
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Human Health and Development
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$25,000
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ICC |
Ocular Transplantation, LLC
Norman Radtke
Jefferson County |
Therapeutic to treat and prevent blindess caused by retinal degenerative diseases
Ocular Transplantation was founded in December 1996 to develop proprietary tools and therapies to treat and prevent blindness caused by retinal degenerative diseases. Proof of concept studies have demonstrated successful integration of donor tissue by the host retina and restoration of visual responses. Currently the tools and methods are being tested in a Phase II Clinical trial to determine efficacy in treating vision loss in patients with age related macular degeneration (AMD) and retinitis pigmentosa (RP). There is no approved therapy to restore vision in patients with the most common form of AMD. Success in this proposed research will impact several important aspects of the treatment of retinal disease, with important economic and clinical ramifications.
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Human Health and Development
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$25,000
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ICC |
US WorldMeds, LLC
P. Breckininridge Jones
Jefferson County |
Lofexidine would be the first non-addictive, non-narcotic treatment approved to relieve the distressing withdrawal symptoms associated with opiate detoxification.”
US WorldMeds has recently announced its launching of a Phase III clinical trial for Lofexidine – which, if accepted by the FDA, would be the first non-addictive, non-narcotic treatment available in the US to treat the debilitating withdrawal symptoms associated with opiate detoxification. Lofexidine has been used to detoxify more than 200,000 opiate addicts in the United Kingdom since its approval 13 years ago. Lofexidine blocks the adrenergic storm created by abrupt cessation of opiates from the body. In contrast, the current mode of treatment for most opiate addicts is methadone or buprenorphine, both of which are replacement (synthetic opiate) drugs, requiring daily administration from licensed detox centers and/or practitioners. There are an estimated 10 million opiate addicts in the US including approximately 1 million heroin addicts, with the remaining addicted to prescription opiates such as Vicodin and Oxycontin. Opiate addiction is worsening in the US as the federal government recently reported that 2.4 million new people began using opiates for non-medicinal purposes in the last year alone. Lofexidine is anticipated to be widely accepted due to being able to be prescribed by any physician and dispensed by any pharmacy anywhere in the US. Lofexidine will enable opiate addicts to safely, effectively and discreetly detoxify without being forced into limited licensed detox centers/clinics for treatment.
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Human Health and Development
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$25,000
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ICC |
EGGCELERATE, LLC
John Beran
Jefferson County |
Novel wound healing product derived from egg shell membrane
Egg shell membranes (ESM) offer enormous potential as a wound dressing because it contains essential nutrients, provides a matrix for new cells and is not subject to the risk of "mad cow disease". ESM is very inexpensive and is essentially a waste product of the food industry. It has not been used for medical applications because it is not soluble and cannot be broken down by the body. Our scientific team has developed a method to convert ESM into a novel dressing that may accelerate wound healing.
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Human Health and Development
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$25,000
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ICC |
AllTranz Inc.
Audra Stinchcomb
Fayette County |
Transdermal Delivery of Cannabidiol
AllTranz is focused on the opportunity to deliver medications through transdermal drug delivery systems. . The product is intended to target pain relief, including nerve-related pain, as well as chronic debilitating muscle spasms, and may impact other conditions like strokes and alcoholism.
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Human Health and Development
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$25,000
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ICC |
AllTranz Inc. 2 THC
Audra Stinchcomb
Fayette County |
Transdermal delivery of tetrahydrocannabinol
AllTranz is focued on the opportunity to deliver medications through transdermal drug delivery systems. Pain management (fentanyl) transdermal patches have been widely accepted but they have very serious GI and respiratory side effects. The company is evaluating new proprietary drug formulations for pain relief in a transdermal delivery system that avoid these side effects. The AllTranz product is intended to target pain relief, primarily nerve-related pain.
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Human Health and Development
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